Well, I digged a little around this issue.
It looks like a patch to the kernel driver of the xradio module is somewhat incomplete.
So I patched the kernel and now the Wi-Fi works like a charm... well, not really (because of the XR819 module) but at least it gets the stored MAC address, as before.
For anyone interested, here is attached the required patch; unfortunately a rebuild of the kernel is needed.
22-05.0-orangepizero-xradio_skupsy_20220520.patch