I have a similar cursor disappearance problem (the mouse still works, I just can't see the cursor icon). This is reproducible by turning the HDMI display off and on again. I also have other severe issues related to power saving, involving a total freeze, but I'm not yet clear as to how to categorize, or how to reproduce this issue.
My build image: Armbian_23.02.0-trunk.0167_Orangepi5_jammy_legacy_5.10.110_xfce_desktop.img.xz
I also, successfully, modified this build to boot off nvme (following the post of Marco Schirrmeister Jan 5) and enabled Ubunutu Gnome/Wayland desktop, gpu acceleration (following the post of Royk Jan 5). Both posts in the "Orange Pi 5 Support" thread.
I also had a problem with my Bluetooth USB adapter, used for headphones, it worked at first but after a few hours (days?), it stopped working. It was fixed by following the instructions of: https://askubuntu.com/questions/1339825/ubuntu-21-04-bluetooth-5-0-dongle-does-not-work-and-says-theres-no-firmware
Note: for the Bluetooth dongle fix, I needed to create symlinks: rtl8761bu_fw.bin -> rtl8761b_fw.bin and rtl8761bu_config.bin -> rtl8761b_config.bin , following the StackExchange comment about renaming for Armbian. I also need to reboot before it worked.