Make sure you have ili9486.ko in your ko module folder: modinfo ili9486 Can you use the DTS that I published in: https://forum.armbian.com/topic/47971-driving-the-ili9488-lcd-40-inch-cheap-chinese-clone/#findComment-208446 But change the "compatible" line with waveshare,rpi-lcd-35 , Delete the stuff under the "compatible" line, until the "}vsync-len = <0>;", and replace it with what you had in your DTS. Change these lines, if they are different: spi-max-frequency = <24000000>; rotate = <270>; bgr; fps = <30>; buswidth = <8>; regwidth = <16>; Reference: https://github.com/raspberrypi/linux/blob/rpi-6.12.y/arch/arm/boot/dts/overlays/piscreen-overlay.dts

then this topic is not applicable

Orange pi 5. In the m.2 slot there is an nvme drive actually.

What hardware do you have? What exactly is in the M.2 slot?

Armbian 25.11.2 Noble XFCE (BSP Kernel: 6.1.115) + PanVk - mesa 26.0 (https://launchpad.net/~ernstp/+archive/ubuntu/mesaaco) + Box64 arm64 v0.4.1 ed9827920 (https://ryanfortner.github.io/box64-debs/) + proton-10.0-4-amd64-wow64 (https://github.com/Kron4ek/Wine-Builds/releases/download/proton-10.0-4/wine-proton-10.0-4-amd64-wow64.tar.xz) + DXVK-stripped v1.6.1 >=60fps@1080p (medium/high settings) box64 environment variables: Hollow Knight